Video teratas

MindAuthors
6 Tampilan · 2 bulan yang lalu

Summary :
⁣M. pumilum has been claimed to protect the bone against the adverse effect of estrogen deficiency. Additionally, it also exhibits anti-diabetic activity. In view of these, this study aims to identify the mechanisms underlying the bone protective effect of M. pumilum in the presence of both estrogen deficiency and diabetes mellitus (DM). Methods: Ovariectomized, diabetic female rats were given M. pumilum leave aqueous extract (MPLA) (50 and 100 mg/kg/day), estrogen, glibenclamide and estrogen plus glibenclamide for 28 consecutive days. At the end of the treatment, fasting blood glucose (FBG), serum insulin, Ca2+, PO4 3- and bone alkaline phosphatase (BALP) levels were measured. Rats were sacrificed and femur bones were harvested for determination of expression level and distribution of RANK, RANKL, OPG and oxidative stress and inflammatory proteins by molecular biological techniques.

About Author :
⁣Dr. Giribabu Nelli, Senior Lecturer in the Department of Physiology, Faculty of Medicine, University of Malaya. In 2011 November, Dr. Giribabu Nelli completed his Ph.D. in reproductive and developmental biology at the Department of Zoology, Sri Venkateswara University, Tirupati, India. From 2013 to 2016, he worked as a postdoctoral fellow at the Department of Physiology, Faculty of Medicine, the University of Malaya. In the same Department, he was recruited as a Senior Lecturer in November 2016. He has now published 61 ISI publications with a high impact factor, as well as two book chapters and two patents (Filed) with achieved 6 grants. His main research interests on diabetes and their complications, obesity, natural products and male and female reproductive physiology.

MindAuthors
6 Tampilan · 3 bulan yang lalu

Summary :
⁣A solid-solid reaction took place at 1000°C during 4 h, using a mixture of pure iron oxide- Fe2O3 and pure zinc oxide – ZnO in order to synthesize zinc ferrite-ZF of different compositions: (S1) Fe2O3/ZnO:3/2, (S2) Fe2O3/ ZnO:1/1, (S3) Fe2O3/ZnO:4/1 and (S4) Fe2O3/ ZnO:2/1. Each of these mixtures were milling during 24 h before the thermic treatment carried out. S1, S2, S3 and S4 samples were became to M1, M2, M3 and M4 samples respectively, which after that were thermally characterized using DSC, DTA and TG techniques. In sequence the ZF produced were examined using XRD, optical and magnetic techniques, SEM & TEM. XRD analysis shows up as contains of equimolar ZF: M3 (73.20%), M4 (28.00%) and M2 (2.10%) as non-stoichiometric phases of ZF: 31.80% of Zn0.95Fe1.78O3.71 and 30.40 % of Zn1.08Fe1.92O4 in M4; Zn0.97Fe2.02O4 in M3 and 35.30% of Zn0.54Fe2.46O4 in M1. Previous studies of magnetic characterization observed a little hysteresis of this equimolar ZF. The results of estimation of the band gap energy (Eg) via the manipulation of the Kubelka-Munk theory allowed to determine that the samples M1, M2, M3 and M4 are considered semiconductors (3.66 and 3.76 eV).


About Author :
⁣Doctor and Master Science in Materials Engineering and Metallurgy by Pontifical Catholic University of Rio de Janeiro- Brazil. Now is a Senior Researcher Professor at Materials Science and Metallurgical Engineering Department of College of Geological, Mining and Metallurgical Engineering - FIGMM of the National University of Engineering-UNI and Chief of Ironmaking and Steelmaking Researcher Group FIGMM UNI. Prof. Gomez-Marroquin is the founding partner and the first president of the board of directors of Metallurgy, Materials and Minerals Peruvian Association-APMMM. Today, she is working in characterizations of different nature biomass such as biochar from olive stone and chicken eggshell for recovering heavy metals from mining wastes. Has been working on the following subjects: recovering metals of Linz Donawitz sludge (LDS), Electric Arc Furnace Dusts (EAFD), and Basic Oxygen Furnace (BOF) using techniques of selfreduction and carbothermic reduction. Also, she had worked in reduction by CO-CO2 mixtures gases of zinc ferrite pure and zinc ferrite present into Electric Arc Furnace Dusts - EAFD using different techniques as such: X-Ray Diffraction (using the Rietveld method), Transmission Electron Microscopy and Scanning Electron Microscopy. About ZF pure and present into EAFD, she has researches that had been onsets with the characterization of the compounds present in EAFD - Iron (III) oxide, zinc oxide & zinc ferrite - using techniques, methodologies, and equipment for thermal characterization (DTA-TGA), structural (XRD), microscopic (SEM-TEM coupled to EDS), physical (briquette porosity, specific gravity, average size & particle specific surface) and chemical analysis by Absorption Atomic and Fluorescence Spectrometer.

MindAuthors
6 Tampilan · 3 bulan yang lalu

Summary :
⁣Flexible, biocompatible electrodes are essential for the development of future wearable and implantable medical devices. While silver nanowire (AgNW) networks are promising candidates for transparent conductive electrodes (TCEs), they suffer from issues such as high roughness, low adhesion, and atmospheric corrosion sensitivity. Many flexible electrodes are made of a wrinkled conductive layer on top of a compliant substrates. Wrinkles provide a way to maintain the integrity and conductivity of the electrode while it is being stretched or bent. In this study, we report on the characterization of semi-transparent electrodes on cellulose nanopaper (CNP) substrates using a plasmaenhanced pulsed laser deposition (PE-PLD) technique. We combined AgNW with titanium nitride (TiN) layers to form wrinkled conducting nano-composite coatings with excellent electromechanical properties. Our results show that the incorporation of AgNW into TiN coatings improves the electrode’s electro-mechanical robustness. Additionally, our data show that CNP/TiNAgNW electrodes exhibit improved stability in air compared to bare AgNW coatings with improved adhesion. These findings have important implications for the development of bio-compatible flexible electronics and could pave the way for the creation of new wearable and implantable medical devices.


About Author :
⁣Dr. Loïk Gence is a professor of the Physics Institute of the PUC university in Chile. He received the B.S., M.S. degree in electrical engineering Engineer from the Catholic University of Louvain and holds a Ph.D. in Applied Sciences from the Ecole Polytechnique de Louvain (2010) under the supervision of Dr. V. Bayot, working on the charge transport properties characterization of low dimensional organic nanostructures. With a background in experimental physics, Dr. L. Gence is specialized in nanomaterials synthesis and characterization with a strong hands-on experience in semiconductor technology and cleanroom environment. His Research experience and interests cover several fields of applied physics from Flexible and Organic electronics, Solar Energy to 2D semiconductor devices.

MindAuthors
6 Tampilan · 3 bulan yang lalu

Summary :
⁣A sterile dressing was devised using a combination of sodium alginate and gelatin as the most suitable polymers along with a small quantity of gellan gum (0.1%), selected out of a range of polymers to co-incorporate a pre-optimised and autoclavable curcumin loaded solid lipid nanoparticles (CSLNs) and live probiotic (Lactobacillus plantarum). The dressing was optimized for polymer concentration and other characteristics using a central composite design. It exhibited a swelling ratio of 412 ± 36%, in vitro degradation time of 3 h, optimal water vapor transmission rate of 1516.81 ± 155.25 g/m2/day, high tensile strength, low-blood clotting index, case II transport, and controlled release of curcumin. XRD indicated strong interaction between employed polymers. FESEM revealed a porous sponge like meshwork embedded with L. plantarum and CSLNs. Polyphenolics like curcumin can improve probiotic effects. Both probiotics (bacteriotherapy) and curcumin promote wound healing via antimicrobial activity, inhibition of pathogenic toxins, immunomodulation, and anti-inflammatory actions. Combination of CSLNs with probiotic enhanced (560%) its antimicrobial effects against planktonic cells and biofilms of skin pathogen, Staphylococcus aureus 9144. The dressing degraded and released L. plantarum, which germinated in the wound bed and exhibited faster wound closure and lowered bioburden in the wound area in mice. This was coupled with a decrease in wound biomarkers and antioxidant enzymes, establishing multiple healing pathways. It was as effective as the silver nanoparticle-based marketed hydrogel dressing; however, the cost and risk of developing resistance would be much lower currently.

About Author :
⁣Dr Indu Pal Kaur is Professor of Pharmaceutics & DPIIT-IPR Chair Professor, Panjab University, Chandigarh, India. Her research forte is enhancing bioperformance of small and large molecules using active-tailored nanoparticles and electrospun scaffolds. Her group is credited with novel nanotechnologies, including 31 filed, out of which 15 Indian and 1 US patent is granted. She is US-Fulbright fellow & has received international beamtime funding at RAL, UK - 2017; 2023. She has received numerous awards including best scientist award twice, IP award, WIPO award for inventors from national and international agencies. She has produced 26 PhDs; ~70 postgraduates; received funding of almost 100 million INR from Government and Industry; delivered >75 Invited Talks; published 155 articles with H index 52.

MindAuthors
6 Tampilan · 3 bulan yang lalu

Summary :
⁣A new and upgraded approach to the diseased states and wellness resulted in a new trend in the healthcare services, namely, personalized and precision medicine (PPM). The latter does need to be drastically and globally re-armed and re-innovated! To achieve the implementation of PPM con-cept, it is necessary to create a fundamentally new strategy based upon the biomarker-guided target-ing and bionavigating to have a unique impact for the implementation of PPM model into the daily Clinical Practice, Biotech and Biopharma. In this sense, despite breakthroughs in research that have led to an increased understanding of PPM-controlled human disease, the translation of discoveries into therapies for patients has not kept pace with medical need. It would be extremely useful to in-tegrate data harvesting from different databanks for applications such as prediction and personali-zation of further treatment to thus provide more tailored measures for the patients and persons-at-risk resulting in improved outcomes and more cost effective use of the latest health care resources including diagnostic (companion ones and/or theranostics), preventive and therapeutic (targeted molecular and cellular) etc. Bio-designers, Bioengineers and Biomanufacturers are beginning to realize the promise of PPM, translating to direct benefit to patients or persons-at-risk. For instance, companion diagnostics tools (CDTs), theranostics and targeted therapies represent important stakes for the Biotech & Biopharma, in terms of market access, of return on investment and of image among the prescribers.


About Author :
⁣A new and upgraded approach to the diseased states and wellness resulted in a new trend in the healthSergey Suchkov was born in the City of Astrakhan, Russia, in a family of dynasty medical doc-tors. In 1980, graduated from Astrakhan State Medical University and was awarded with MD. In 1985, Suchkov maintained his PhD as a PhD student of the I.M. Sechenov Moscow Medical Academy and Institute of Medical Enzymology. In 2001, Suchkov maintained his Doctor De-gree at the National Institute of Immunology, Russia. From 1989 through 1995, Dr Suchkov was being a Head of the Lab of Clinical Immunology, Helmholtz Eye Research Institute in Moscow. From 1995 through 2004 - a Chair of the Dept for Clinical Immunology, Moscow Clinical Re-search Institute (MONIKI). In 1993-1996, Dr Suchkov was a Secretary-in-Chief of the Editorial Board, Biomedical Science, an international journal published jointly by the USSR Academy of Sciences and the Royal Society of Chemistry, UK.care services, namely, personalized and precision medicine (PPM). The latter does need to be drastically and globally re-armed and re-innovated! To achieve the implementation of PPM con-cept, it is necessary to create a fundamentally new strategy based upon the biomarker-guided target-ing and bionavigating to have a unique impact for the implementation of PPM model into the daily Clinical Practice, Biotech and Biopharma. In this sense, despite breakthroughs in research that have led to an increased understanding of PPM-controlled human disease, the translation of discoveries into therapies for patients has not kept pace with medical need. It would be extremely useful to in-tegrate data harvesting from different databanks for applications such as prediction and personali-zation of further treatment to thus provide more tailored measures for the patients and persons-at-risk resulting in improved outcomes and more cost effective use of the latest health care resources including diagnostic (companion ones and/or theranostics), preventive and therapeutic (targeted molecular and cellular) etc. Bio-designers, Bioengineers and Biomanufacturers are beginning to realize the promise of PPM, translating to direct benefit to patients or persons-at-risk. For instance, companion diagnostics tools (CDTs), theranostics and targeted therapies represent important stakes for the Biotech & Biopharma, in terms of market access, of return on investment and of image among the prescribers.

MindAuthors
6 Tampilan · 3 bulan yang lalu

Summary :
⁣To enhance the lifetime of mechanical system such as automobile, new reliability methodology – parametric Accelerated Life Testing (ALT) – suggests to produce the reliability quantitative (RQ) specifications— mission cycle—for identifying the design defects and modifying them. It incorporates: (1) a parametric ALT plan formed on system BX lifetime that will be X percent of the cumulated failure, (2) a load examination for ALT, (3) a customized parametric ALTs with the design alternatives, and (4) an assessment if the system design(s) fulfil the objective BX lifetime. So we suggest a BX life concept, life-stress (LS) model with a new effort idea, accelerated factor, and sample size equation. This new parametric ALT should help an engineer to discover the missing design parameters of the mechanical system influencing reliability in the design process. As the improper designs are experimentally identified, the mechanical system can recognize the reliability as computed by the growth in lifetime, LB, and the decrease in failure rate. Consequently, companies can escape recalls due to the product failures from the marketplace. As an experiment instance, two cases were investigated: 1) problematic reciprocating compressors in the French-door refrigerators returned from the marketplace and 2) the redesign of hinge kit system (HKS) in a domestic refrigerator. After a customized parametric ALT, the mechanical systems such as compressor and HKS with design alternatives were anticipated to fulfil the lifetime – B1 life 10 year.


About Author :
⁣Dr Woo has a BS and MS in Mechanical Engineering, and he has obtained PhD in Mechanical Engineering from Texas A&M. He majors in energy system such as HVAC and its heat transfer, optimal design and control of refrigerator, reliability design of thermal components, and failure Analysis of thermal components in marketplace using the Non-destructive such as SEM & XRAY. In 1992.03–1997 he worked in Agency for Defense Development, Chinhae, South Korea, where he has researcher in charge of Development of Naval weapon System. He was working as a Senior Reliability Engineer in Refrigerator Division, Digital Appliance, SAMSUNG Electronics. Now he is working as associate professor in mechanical department, Ethiopian Technical University.

MindAuthors
6 Tampilan · 3 bulan yang lalu

Summary :
⁣Two-dimensional (2D) materials have shown great promise in next-generation devices due to their atomic thinness and broad electronic properties. To realize these post-silicon electronics, it will be necessary to electrically connect these 2D materials both in- and out-ofplane. However, the lattice mismatch between these atomic membranes leads to unavoidable strain, dislocations, or ripples, which can strongly affect the mechanical, electronic, and optical properties. This presentation will discuss using state-of-the-art four-dimensional scanning transmission electron microscopy (4D-STEM) techniques to address how different 2D materials merge to form lateral heterostructures. The study has enabled discoveries of the intricate and complex interface structures unique to 2D materials. Subsequent control or engineer of these deformations can profoundly impact future material and device development.


About Author :
⁣Dr. Han is an assistant professor of Materials Science and NanoEngineering. She received her B.S. in Physics from Tsinghua University and Ph.D. in Applied Physics from Cornell with Prof. David Muller. Her research focused on electron microscopy and the characterization of nanomaterials. After graduating from Cornell University, she joined Prof. Nieng Yan’s group in the Department of Molecular Biology at Princeton University to expand her knowledge on cryo-EM, as well as develop ways to utilize nanomaterials in biological characterization. Dr. Han started her own lab in the Department of Materials Science and NanoEngineering at Rice University in July 2020. Her group has a focus on developing novel TEM techniques to investigate nanomaterials and nano-bio interfaces.

MindAuthors
6 Tampilan · 3 bulan yang lalu

Summary :
⁣An experimental study of the graphene conductivity in an aqueous environment is carried out in this study. The presence of a time dependence of the graphene resistivity in water is established. In addition, the characteristic relaxation times of resistivity are determined when graphene is immersed in water and then dried. The resistivity temperature dependence is used to estimate the values of the band gap arising in graphene due to water contact. Based on the analysis of molecular dynamics modeling data, a possible mechanism responsible for the opening of the band gap in graphene is proposed. This mechanism is associated with the inhomogeneous tangential electric field appearance in the plane of the graphene flake, caused by water molecules structured near the graphene surface.


About Author :
⁣Vladimir Andryushchenko, Senior Lecturer, Department of Physics, Novosibirsk State University, conducted his PhD in Institute of Thermophysics, Russia. Now he has been studying on mechanistic aspects of fluid structuring near different objects: graphene, nanotubes, nanoparticles. He is also interested in molecular dynamics modeling of protein folding.

MindAuthors
6 Tampilan · 3 bulan yang lalu

Summary :
⁣In recent years, due to its remarkable physicochemical properties, graphene has attracted attention in electrochemical reactions such as the hydrogen evolution reaction (HER) for hydrogen production [1,2]. Graphene can be prepared by efficient reduction of graphene oxide structure. In this study, the effect of oxidation time and graphite precursors on the formation of graphene oxide structure by Hummers’ method was investigated. Graphene oxide samples prepared with oxidation times of 24-72 h using two different graphite precursors (20μm and 150μm) were denoted as GO-2024, GO- 2048, GO-2072, and GO-15048. In the XRD patterns of GO-2024, GO-2048 and GO-2072 samples, the oxidation peaks of graphite were observed

About Author :
⁣I am Seyda UZUN. In 2021, I graduated from Gazi University, Faculty of Engineering, Chemical Engineering Department. During my university and high school life, besides my academic education, I participated in many conferences and seminars that will contribute to my career life and took part in certificate programs. Currently, within the scope of the TUBITAK project, we get support for our project with my dear advisor Dr. Dilsad Dolunay ESLEK KOYUNCU, and together with my advisor, we are working on developing catalysts for hydrogen evolution reaction (HER).

MindAuthors
6 Tampilan · 3 bulan yang lalu

Summary :
⁣We consider the effects of the external static magnetic field on the electronic and physical properties in the excitonic AA-stacked bilayer graphene. We have considered the effect of coupling between the magnetic field B and the spins $\sigma$, which results in the phase modulation of the particles in the system or the spin-dependent magnetic field $B_{\sigma}$. We have constructed the wave strings attached to the particles, for each given periodic interval of the phases, governed by spins. We have calculated the electronic band structure of the AA-bilayer, in the presence of transverse magnetic field and we have found the Metal-Semiconductor-Insulator transition in the AA-bilayer graphene, governed by the strength of applied magnetic field. The spins in our problem are considered as localized along the direction of applied field or opposite to it. The transition into Dirac’s spectrum of usual graphene is also discussed at certain band structure parameters regimes.

About Author :
⁣Dr Vardan Apinyan works at the Institute of Low Temperature and Structure Research (ILTSR), in the group of Condensed Matter Theory. He has completed his PhD studies at the International Max Planck Research School in Dresden-Wrocław in November 2010, and he was displaced definitively to Wrocław, in December 2011. Now, he is working on many subjects in condensed matter physics like electron transport in graphene-based heterostructures, excitonic physics in graphene heterostructures, mathematical aspects in the physics of graphene. He is elaborating new theoretical methods to describe the electronic correlations and band structures in graphene-based heterojunctions. Dr Vardan Apinyan described the possibility of the passage from the metallic state into the insulator state in the AA stacked bilayer graphene structure.

MindAuthors
6 Tampilan · 3 bulan yang lalu

Summary :
⁣The primary aim of this study was to determine the prevalence of pelvic dysfunction symptoms following OASI. The secondary aim was to assess the scope of a dedicated perineal trauma clinic in identifying and investigating women that have experienced faecal incontinence after OASI and if a transitional clinic arrangement to colorectal or continence services would be useful.


About Author :
⁣An Obstetrics and Gynaecology doctor who is deeply passionate about patient education and women’s health. She believes empowering patients to be confident & knowledgeable about their conditions builds physician-patient relationships and improves patient outcomes. Someday, she would love to get involved in medical volunteering and her family loves globetrotting . Thanks to these travel goals she has moved a lot of countries - Born in India , did her schooling in Dubai , went back to India for med school and residency in Ob Gyn ( Civil Hospital , Ahmedabad ) , moved to the UK for a Royal college fellowship and worked in the UK for 3 years and has just moved back to Dubai and am working with the Medcare Hospital Group . She has advanced training in Maternal medicine , Urogynaecology and Menopause and is accredited by the european board in aesthetic gynaecology.

MindAuthors
6 Tampilan · 3 bulan yang lalu

Summary :
⁣Hemorrhagic ascites associated with pleural effusion due to endometriosis is an uncommon presentation rarely reported in the medical literature. We present a case of a 29-year-old woman with a history of primary infertility .She presented to the emergency department for asthenia, abdominal swelling and pain. On examination she was stable with signs of massive ascites and right-sided pleural effusion. This was confirmed on ultrasound scan and computed tomography. A magnetic resonance imaging was performed to define the nature of fluid .It shows an abundant ascites (figure a) and right pleural effusion (figure b) seen as hyperintense signal on T1 weighted sequences due to hematic component. Paracentesis was done reveling a bloody ascetic fluid. She declined a pleurodesis for the pleural effusions. The patient was treated with a GnRH analogues with progressive reduction of pleural effusion This report of case draws attention to this presentation as a complication of endometriosis. This suggests that clinicians should include endometriosis in the differential diagnoses of middle-age women presenting with bloody ascites and pleural effusion in addition to infection and malignancy.

About Author :
⁣Hind Ennasser a resident doctor in the 5th year of residency at Department of Obstetrics and Gynecology, Mohammed VI University Hospital Center, Oujda Morocco

MindAuthors
6 Tampilan · 3 bulan yang lalu

Summary :
⁣Anti-N-Methyl-D-Aspartate encephalitis is a subcategory of auto-immune encephalitis. It is known for its aggressive presenting symptoms and rapid deterioration, yet it is treatment responsive. It is associated in 50% to ovarian teratoma. Anti-NMDA receptor encephalitis with ovarian teratoma is a rare entity with rapid deterioration. Early diagnosis, surgical resection and proper medical treatment are essential for the management of this disease. We will report 2 cases of Anti-NMDA encephalitis with review of literature and discussion over treatment modalities.

MindAuthors
6 Tampilan · 3 bulan yang lalu

Summary :
⁣A total of 12RCTs with 2028 women (hysterectomy: n=977 women vs E:A/R: n = 1051 women) were included. Hysterectomy was compared with only endometrial ablation in five studies and only endometrial resection in five studies and both ablation and resection in two studies. Meta-analysis found that women in the hysterectomy group were more likely to show patient-reported and objective outcomes improving in HMB comparing with EA/R (risk ratio(RR)0.75, 95%CI:0.71,0.79) and (MD44.00, 95%CI:36.09,51.91)respectively. Patient-satisfaction was higher after hysterectomy up-to 2-years follow-up, (RR:0.90, 95%CI:0.86,0.94) but this effect was absent with longer term followup. EA/R had lower risk of adverse-outcomes for sepsis (RR:0.03, 95%CI:0.00,0.56), wound infection (RR:0.05, 95%CI:0.01,0.28) and urinary tract infection (RR:0.20,95%CI:0.10, 0.42) but higher risk of fluid-overload (RR:7.80,95%CI:2.16,28.16) and perforation (RR:5.42,95%CI:1.25,23.45).


About Author :
⁣Alyaa graduated in Medicine at Faculty of Medicine Kasr Al Ainy - Cairo University in 1997 and had training in obstetrics and gynaecology, then joined the University of Aberdeen in 2009.Currently she is a clinical lecturer and research fellow in urogynecology following obtaining of her MD in 2014. She is interested in medical education and obtained diploma in medical education 2016. She supervises students’ medical elective and intercalated BSc projects. Currently, Alyaa is Year 1 Deputy Lead Coordinator and Year 1 OSCE lead. Also, she is coordinator for “women’s health in a global setting online course” and Alyaa is a member of the Aberdeen Centre for Women’s Health Research and focuses on improving women’s health.

MindAuthors
6 Tampilan · 3 bulan yang lalu

Summary :
⁣During the fetal period, the embryonal premature central nervous system (CNS) structure rapidly develops into a mature structure with gyral formation. Within this rapid development, various developmental disorders and insults result in multiple phenotypes of fetal CNS abnormalities. For understanding fetal CNS diseases, basic knowledge of the development of the central nervous system is essential. Malformations of cortical development (MCD) are disorders of cerebral cortex formation caused by various genetic mutations, infections, vascular abnormalities, or metabolic abnormalities. MCD is associated with abnormal cortical structure, ectopic gray matter, odd brain size.


About Author :
⁣Ritsuko K. Pooh graduated from Law and Medical Departments. As an Obstetrician, she dedicated to clinical investigation on embryos and fetal brain in perinatology. Especially, she introduced sophisticated fetal neuroimaging. She established CRIFM Prenatal Medical Clinic (https://fetal-medicine-pooh.jp/en/). Her Neurosonograms are really scientific/artistic, and displayed at NIH in USA. She received the Alfred Alfred Kratochwil Award, Lifetime Achievement Award, and Sir William Liley medal. She published 173 articles and 4 books. She established the clinical genetic laboratory (Ritz Medical Co., Ltd.) for performing latest genetic examination. She is a truly one of the international executives in perinatology.

MindAuthors
5 Tampilan · 2 bulan yang lalu

Summary :
⁣Diabetes mellitus, a major lifestyle disease, has become a global burden. The International Diabetes Federation (IDF), Diabetes Atlas (2015), reports that there are 415 million people diagnosed with diabetes representing 8.8% of adults aged 20–79 years. A knowledge on oral lesions to help diagnose a case of diabetes which would also require a referral to endocrinologist. Also a 2 way link has been established between diabetes & periodontitis. A physician/endocrionologist/diabetologist needs to be aware of oral changes to be able to form an interdisplinary unit for a comprehensive handling of patients. An awareness of periodontitis as the 6th Complication of Diabetes is also important. Dental caries/periodontitis, black hairy tongue, candidiasis, Xerostomia & other mucosal lesions are also a frequent finding in diabetic patients. A knowledge on the oral changes and its entity in diabetic complications stresses the importance of dental element in diabetes.

About Author :
⁣She is a Reader in the Department of periodontology, JSSDCH, JSSAHER with 20 years experience. She has authored national and international publications. She has presented papers nationally and internationally, won nationally and international awards. She is a Laser Specialist from SOLA, University of Vienna. She is an implantolgist. She has been a Speaker in National Conferences. She is the Team Leader of Special Interest Group “Diabetes & Oral Care.” She is a member of Geriatric clinic at JSS Multi Speciality Hospital. She is a reviewer in various journals. She has been a chairperson, judge/panelist at conferences. She has organized various webinars/conferences/epaper/eposter competitions. he is a member at various Dental societies. She has authored a book. She has guided Undergraduates/postgraduate research/paper presentations, winning awards.

MindAuthors
5 Tampilan · 3 bulan yang lalu

Summary :
⁣A series of alloy system take place in a class of functional materials due to stimulus response to external effect. Shape memory alloys take place in this group by exhibiting a peculiar property called shape memory effect. This phenomenon is characterized by the recoverability of two certain shapes of material at different conditions. Shape memory effect is initiated with thermomechanical processes on cooling and deformation, and performed thermally on heating and cooling, with which shape of the materials cycle between original and deformed shapes in reversible way. Therefore, this behavior can be called Thermal Memory or Thermoelasticity. This deformation is plastic deformation, due to the soft character of the material in low temperature condition, deformation energy is stored in the material and released on heating by recovering the original shape. These alloys are used as shape memory devices in many fields such as medicine, metallurgy, building industry. This property is result of two displacive transformations, thermal and stress induced martensitic transformations. Thermal induced martensitic transformation occurs on cooling with cooperative movements of atoms by means of lattice invariant shears in <110 > -type directions on the {110} - type planes of austenite matrix, along with lattice twinning and ordered parent phase structures turn into the twinned martensite structures. Twinned structures turn into the detwinned structures by means of stress induced martensitic transformation, by stressing material in the martensitic condition. Atomic movements are confined to the neighbor atom distances, and martensitic transformations are diffusionless or displacive transformations.


About Author :
⁣Dr. Adiguzel graduated from Department of Physics, Ankara University, Turkey in 1974 and received PhD- degree from Dicle University, Diyarbakir-Turkey. He has studied at Surrey University, Guildford, UK, as a post- doctoral research scientist in 1986-1987, and studied were focused on shape memory effect in shape memory alloys. His academic life started following graduation by attending an assistant to Dicle University in January 1975. He became professor in 1996 at Firat University in Turkey, and retired on November 28, 2019, due to the age limit of 67, following academic life of 45 years. He supervised 5 PhD- theses and 3 M. Sc- theses and published over 80 papers in international and national journals; He joined over 120 conferences and symposia in international level with contribution. He served the program chair or conference chair/co-chair in some of these activities. Also, he joined in last six years (2014 - 2019) over 60 conferences as Keynote Speaker and Conference Co-Chair organized by different companies. Additionally, he joined over 120 online conferences in the same way in pandemic period of 2020-2022. Dr. Adiguzel served his directorate of Graduate School of Natural and Applied Sciences, Firat University, in 1999- 2004. He received a certificate awarded to him and his experimental group in recognition of significant contribution of 2 patterns to the Powder Diffraction File – Release 2000. The ICDD (International Centre for Diffraction Data) also appreciates cooperation of his group and interest in Powder Diffraction File.

MindAuthors
5 Tampilan · 3 bulan yang lalu

Summary :
⁣Twenty two RNA therapies reached the medical market by Q1 2023. Targeted intracellular delivery remains the key requirement. For refinements of nanocarriers we focus on a bioinspired, sequence-defined process including (i) artificial amino acids (ii) precise assembly into sequences by solid phase-assisted synthesis (iii) screening for delivery and selection of top candidates. A recent chemical evolution library combined aminoethylene amino acids as polar protonatable units with novel lipo amino fatty acids (LAFs) as hydrophobic protonatable motifs. These novel double pH-responsive nucleic acid carriers utilize intracellular delivery mechanisms of both cationizable lipids and cationic polymers. The endosomal pH-dependent tunable polarity of LAF was successfully implemented by a central tertiary amine, which disrupts the hydrophobic character once protonated, resulting in drastic pH-dependent change in the logarithmic (octanol/ water) distribution logD from around +1 (pH 7.4) to -1 (pH 5.5). This “molecular chameleon character” turned out to be advantageous for mRNA, siRNA or CRISPER/Cas9 sgRNA delivery. The efficiency of best performers was up to several 100-fold higher compared to previous carriers. Transfection activity of mRNA lipoplexes was maintained even in the presence of 90% serum and at extremely low dosage of 3 pg mRNA (~2 nanoparticles/cell), in the range of the viral potency. mRNA lipoplexes showed great in vivo performance in mice with high expression levels in spleen, tumor, lung, and liver upon intravenous administration of 1 μg luciferase mRNA.


About Author :
⁣Ernst Wagner is professor of Pharmaceutical Biotechnology and Center of NanoScience at LMU Munich since 2001. From 1992-2001 he was Director Cancer Vaccines, Boehringer Ingelheim (first polymer-based gene therapy trial in 1994), 1987-1995 group leader at IMP Vienna and Vienna University Biocenter, 1985-1987 postdoc at ETH Zurich, in 1985 PhD in chemistry (TU Vienna). He is Academician of European Academy of Sciences, member of CRS College of Fellows, Board member of German Society for Gene Therapy. He has authored 500 publications, with 50 503 citations, h-index 112 (GS).

MindAuthors
5 Tampilan · 3 bulan yang lalu

Summary :
⁣MoS2 monolayer, a prototypical transition metal dichalcogenide (TMD), with high carrier mobility and apt optical properties have often been used in photocatalysis. Janus (MoSSe) too follows the same. However, the usage of these monolayers is limited by the carrier (e- -h+) recombination, making it imperative to examine their bilayer van der Waals heterostructure (vdW HTS), where the spatial separation of e--h+ on two layers reduce recombination. The design of bilayer vdW HTSs here, consists of TMDs (HfS2, ZrS2, TiS2, WS2) and transition metal oxides (TMOs) (HfO2, T-SnO2, T-PtO2). The present work displays curiosity in their Z-scheme photocatalytic capability, where faster interlayer e--h+ recombination as compared to that of intralayer, is required for efficient spatial charge separation and hence, redox reactions. We have performed first-principles based calculations under the framework of (hybrid) density functional theory (DFT) and manybody perturbation theory (GW approximation), to obtain the band edge levels and optical spectra, respectively.


About Author :
⁣Ms. Arunima Singh is pursuing Ph.D. in the Department of Physics, IIT Delhi since July 2018. She works in the field of 2D materials and van der Waals heterostructures (vdW HTSs). Her material designs aim to have significant impact in the environment. She uses first principles-based simulation for analyzing the same, by integrating different level of theories starting from state-of-the-art density functional theory (DFT) to highly sophisticated quantum chemistry methods (viz. GW, BSE, etc.). She has been interested in the probable point defects formed in MoS2 monolayer that can tune the band gap for feasible optoelectronic applications. Moreover, she has been working on MoS2 and MoSSe (Janus) based van der Waals heterostructures (vdW HTSs), for optoelectronic, photocatalytic and electrocatalytic applications.

MindAuthors
5 Tampilan · 3 bulan yang lalu

Summary :
⁣⁣MoS2 monolayer, a prototypical transition metal dichalcogenide (TMD), with high carrier mobility and apt optical properties have often been used in photocatalysis. Janus (MoSSe) too follows the same. However, the usage of these monolayers is limited by the carrier (e- -h+) recombination, making it imperative to examine their bilayer van der Waals heterostructure (vdW HTS), where the spatial separation of e--h+ on two layers reduce recombination. The design of bilayer vdW HTSs here, consists of TMDs (HfS2, ZrS2, TiS2, WS2) and transition metal oxides (TMOs) (HfO2, T-SnO2, T-PtO2). The present work displays curiosity in their Z-scheme photocatalytic capability, where faster interlayer e--h+ recombination as compared to that of intralayer, is required for efficient spatial charge separation and hence, redox reactions. We have performed first-principles based calculations under the framework of (hybrid) density functional theory (DFT) and manybody perturbation theory (GW approximation), to obtain the band edge levels and optical spectra, respectively.


About Author :
⁣Ms. Arunima Singh is pursuing Ph.D. in the Department of Physics, IIT Delhi since July 2018. She works in the field of 2D materials and van der Waals heterostructures (vdW HTSs). Her material designs aim to have significant impact in the environment. She uses first principles-based simulation for analyzing the same, by integrating different level of theories starting from state-of-the-art density functional theory (DFT) to highly sophisticated quantum chemistry methods (viz. GW, BSE, etc.). She has been interested in the probable point defects formed in MoS2 monolayer that can tune the band gap for feasible optoelectronic applications. Moreover, she has been working on MoS2 and MoSSe (Janus) based van der Waals heterostructures (vdW HTSs), for optoelectronic, photocatalytic and electrocatalytic applications.




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