Palladium Iodide Catalyzed Carbonylative Synthesis of Heterocycles | Bartolo Gabriele |
Summary :
In this Keynote, I will present the recent achievements realized by my research group in the catalytic synthesis of heterocyclic derivatives by palladium-iodide promoted carbonylation processes. It will be shown how a simple catalytic system, consisting of PdI2 in conjunction with an excess of KI and in the absence of additional ligands, is able to promote a plethora of carbonylation reactions, including oxidative and substitutive carbonylations. Starting from CO and simple organic substrates (functionalized alkynes, in particular) as building blocks, these processes have allowed obtaining carbonylated heterocycles in one single synthetic step under relatively mild reaction conditions.
About Author :
Prof. Bartolo Gabriele completed his PhD in “Chemical Sciences” in 1994 at the University of Calabria (Unical). In 1997 he joined Professor Ronald Breslow’s group at Columbia University (New York) for 1 year as a NATO-CNR fellow. In 1998 he returned to Unical, where he was promoted to Full Professor in 2006. His current scientific production includes more than 210 articles in international peer-reviewed journals [h-index: 48; total citations: 7048 (Scopus)] more than 10 chapters in international books, and 20 industrial patents. He received the “Research Award” in 2013 from the Italian Chemical Society, in the field Synthetic Organic Chemistry. His current research interests include the synthesis of high value added molecules by catalytic techniques and the development of new materials for advanced applications.
