Kawasaki disease in children | Dmytro Tokariev |
Summary :
Kawasaki disease, since its first description in the 60s of the 20th century, has always been of particular interest to pediatricians around the world, due to the ploimorphism of the clinical picture, unpredictable course and possible complications in the form of coronaritis, aneurysms of the coronary arteries and the possibility of an early debut of the lesion. hearts. Your attention is given to the case of Kawasaki disease in a 4-year-old girl. The child was transfused intravenous immunoglobulin once at a dose of 2 g/kg, after which the child received acetylsalicylic acid at a dose of 85 mg/kg/day (80-100 mg/kg/day). Against the background of ongoing treatment, there was a disappearance of fever and an unexpectedly rapid decrease in the manifestations of coronaritis - a decrease in the diameter of the coronary arteries, according to ultrasound of the heart. However, the first attempts to reduce the dose of acetylsalicylic acid, after 3 days of a feverfree period, to a maintenance dose of 3-5 mg/ kg/day, led to a relapse of fever. Considering this clinical picture, the child was re-administered acetylsalicylic acid in doses of 85 mg/kg/day, and then a decision was made to gradually reduce the dose of acetylsalicylic acid: 85 mg/kg/day - 50 mg/kg/day-25 mg/kg/day. day-5mg/kg/day. With this appointment, the recurrence of fever was not observed. The child was discharged home in a satisfactory condition. Control ultrasound examination after 2 weeks showed a significant regression of the diameters of the coronary arteries. Continues therapy with acetylsalicylic acid 5 mg / kg / day - an estimated duration of 12 weeks and continues to be regularly monitored by a pediatrician and cardiologist.
About Author :
Dmytro Tokariev received a medical degree at the age of 23 from the Dnepropetrovsk State Medical Academy, Ukraine. He was a neonatologist at the Regional Neonatal Center, Dnipro, Ukraine, medical director of the research company Arensia Exploratory Medicine Ukraine., Kiev, Ukraine, pediatrician in Amel Dental Clinic, Dnipro, Ukraine. Now he is a head of Pediatric Department Children’s and Maternal Hospital named after Prof. M.F. Rudnev, Dnipro, Ukraine. He has publications devoted to the problems of neonatology, pediatrics, clinical genetics, in particular to the problems of CDG. He is the co-author (another author is Alexandr Kulikov) of the medical diagnostic program Neo Genetics (Interactive database including clinical information on more than 2,500 genetic syndromes with an innovative search engine using about 8,000 symptoms
