Extravasation in children | Dr.Mary Anbarasi Johnson |

Summary :
⁣Extravasation is a major problem especially among the pediatric population. Extravasation is defined as infiltration or leakage of an intravenous chemotherapeutic agent into the surrounding tissue which results in local damage.The various types of extravasation causing agents can be Sclerosing,fibrosing agents.Drugs that can cause blisters,ulceration, severe tissue destruction & necrosis. Eg.. Vincristine.or drugs that can cause burning and inflammation.eg.. Dacarbazine. Usually cause extravasation. Two major mechanisms are believed to cause tissue damage,DNA binding vesicant agents (e.g., anthracyclines) Absorbed by local cells in the tissue and bind to DNA,causing cell death.Non DNA binding vesicant agents (e.g., vinca alkaloids)These agents do not bind to cellular DNA.Local tissue damage is more easily neutralized than damage to surrounding tissues. Pediatric nurses play a major role in preventing extravasations occurring and also managing the extravasations on time to prevent complications which even can be fatal.The aim of this presentation is to high light the role of nurses in preventing and managing extravasations in the hospital.


About Author :
⁣Mary Anbarasi Johnson working as a professor and Head in pediatric nursing department ,CMC Vellore.I worked as Clinical Nurse Specialist in PICU for a year and as Assit Professor in USA for two years.I also worked in administration in nursing ,in Saudi Arabia Defence Sector. CMC gave me opportunity to be Master trainer for International Projects like GFATM ,IMNCI at national level aswell national projects like ICMR Infection control ,Child Sexual Abuse Protection ,OSCE by Dr.MGR Medical university aswell Diabetic Educators programme etc. It also gave me opportunity to be examiner or paper setter for various levels of nursing students for 6 universities and inspector for Dr.MGR Medical University .I am very much interested in reviewing articles.I have published in 70 national , international journals and presented in around 30 national and international conferences. I have also contributed for 5 book chapters and is working on publishing a book soon. I have served in CMC Vellore as addl.Deputy Nurisng Superintendent for staff training and quality assurance aswell in CMC Instituitional research board as a member for a term of 4 years.I am reviewer or editorial member or advisory member in more than 50 international journals.I am also a reciepient of President”s Gold medal for standing first in the university for Bsc.N programme .I give all thanks to Lord Jesus Christ who is the reason for my living.I am indepted to my family ,teahcers and friends for their encouragement and support and particularly to CMC Vellore which has mentored me.